Name: John Isner
Country: USA
Birthdate: 26.04.85, 39 years
Height: 205 cm
Weight: 107 kg
Profi since: 2007
Right-handed
ATP ranking: 307
TOP ranking's position: 8 (16.07.18, 3720 points)
Points: 175
Prize money: 22430808 $
Matches total: 920
Win: 563
%: 61.2 %
Country: USA
Birthdate: 26.04.85, 39 years
Height: 205 cm
Weight: 107 kg
Profi since: 2007
Right-handed
ATP ranking: 307
TOP ranking's position: 8 (16.07.18, 3720 points)
Points: 175
Prize money: 22430808 $
Matches total: 920
Win: 563
%: 61.2 %
| year | summary | Hard | Clay | I. hard | Carpet | Grass | Acrylic |
| 2023 | 9/14 | 2/9 | 0/2 | 4/1 | 0/0 | 3/2 | 0/0 |
| 2022 | 23/18 | 9/10 | 7/4 | 3/2 | 0/0 | 4/2 | 0/0 |
| 2021 | 23/14 | 18/8 | 5/2 | 0/3 | 0/0 | 0/1 | 0/0 |
| 2020 | 11/11 | 9/8 | 2/2 | 0/1 | 0/0 | 0/0 | 0/0 |
| 2019 | 30/18 | 22/14 | 0/0 | 3/3 | 0/0 | 5/1 | 0/0 |
| 2018 | 34/24 | 16/9 | 8/5 | 5/9 | 0/0 | 5/1 | 0/0 |
| 2017 | 39/23 | 20/12 | 7/4 | 6/4 | 0/0 | 6/3 | 0/0 |
| 2016 | 33/21 | 16/11 | 5/5 | 7/3 | 0/0 | 5/2 | 0/0 |
| 2015 | 48/26 | 26/10 | 10/6 | 8/7 | 0/0 | 4/3 | 0/0 |
| 2014 | 40/23 | 28/14 | 6/5 | 2/2 | 0/0 | 4/2 | 0/0 |
| 2013 | 39/26 | 22/12 | 8/5 | 5/6 | 0/0 | 4/3 | 0/0 |
| 2012 | 45/21 | 24/9 | 10/7 | 3/3 | 0/0 | 8/2 | 0/0 |
| 2011 | 39/22 | 22/10 | 4/7 | 7/4 | 0/0 | 6/1 | 0/0 |
| 2010 | 39/26 | 22/9 | 8/10 | 8/6 | 0/0 | 1/1 | 0/0 |
| 2009 | 41/23 | 31/15 | 4/2 | 6/6 | 0/0 | 0/0 | 0/0 |
| 2008 | 26/25 | 19/14 | 4/5 | 2/2 | 0/0 | 1/4 | 0/0 |
| 2007 | 32/13 | 22/7 | 0/0 | 8/4 | 2/1 | 0/1 | 0/0 |
| 2006 | 5/4 | 5/4 | 0/0 | 0/0 | 0/0 | 0/0 | 0/0 |
| 2005 | 7/4 | 7/4 | 0/0 | 0/0 | 0/0 | 0/0 | 0/0 |
| 2004 | 0/1 | 0/1 | 0/0 | 0/0 | 0/0 | 0/0 | 0/0 |
| TOTAL | 563/357 | 340/190 | 88/71 | 77/66 | 2/1 | 56/29 | 0/0 |
| perc. % | 61.2 % | 64.15 % | 55.35 % | 53.85 % | 66.67 % | 65.88 % | 0 % |
John Isner / scheduled / last
| no matches found |
John Isner form / surface: Hard
John Isner / surface: Hard
| 31.08.23 | 2nd round | Michael Mmoh | John Isner | 3-6, 4-6, 7-63, 6-4, 7-67 |  | match details |  New York | Hard |
| 29.08.23 | 1st round | John Isner | Facundo Diaz Acosta | 6-4, 6-3, 7-61 |  | match details | ||
| 14.08.23 | 1st round | Jordan Thompson | John Isner | 7-65, 7-62 | | match details | Cincinnati | Hard |
| 02.08.23 | 2nd round | Stefanos Tsitsipas | John Isner | 6-2, 6-4 | | match details |  Los Cabos | Hard |
| 31.07.23 | 1st round | John Isner | Rinky Hijikata | 6-2, 7-64 | | match details | ||
| 25.07.23 | 1st round | Dominik Koepfer | John Isner | 3-6, 7-64, 7-63 | | match details | Atlanta | Hard |
| 22.03.23 | 1st round | Emilio Nava | John Isner | 7-65, 7-64 | | match details | Miami | Hard |
| 08.03.23 | 1st round | Brandon Nakashima | John Isner | 7-67, 6-3 | | match details | Indian Wells | Hard |
| 27.02.23 | 1st round | Taylor Harry Fritz | John Isner | 3-6, 6-3, 6-4 | | match details | Acapulco | Hard |
| 18.01.23 | 1st round | Adrian Mannarino | John Isner | 6-75, 7-68, 6-2, 6-2 | | match details |  Melbourne | Hard |
| 10.01.23 | 1st round | Gregoire Barrere | John Isner | 6-73, 7-65, 6-3 | | match details |  Auckland | Hard |
| 01.09.22 | 2nd round | Holger Rune | John Isner | John Isner - walk over | | match details | New York | Hard |
| 30.08.22 | 1st round | John Isner | Federico Delbonis | 6-3, 6-1, 7-5 | | match details | ||
| 19.08.22 | 1/4 | Stefanos Tsitsipas | John Isner | 7-65, 5-7, 6-3 | | match details | Cincinnati | Hard |
| 18.08.22 | 3rd round | John Isner | Sebastian Korda | 7-63, 1-6, 7-64 | | match details | ||
| 17.08.22 | 2nd round | John Isner | Hubert Hurkacz | 7-65, 6-75, 6-2 | | match details | ||
| 15.08.22 | 1st round | John Isner | Benjamin Bonzi | 7-611, 3-6, 7-64 | | match details | ||
| 29.07.22 | 1/4 | Jenson Brooksby | John Isner | 3-6, 6-1, 6-4 | | match details | Atlanta | Hard |
| 28.07.22 | 2nd round | John Isner | Ben Shelton | 7-68, 4-6, 7-63 | | match details | ||
| 25.03.22 | 2nd round | Hugo Gaston | John Isner | 7-65, 6-4 | | match details | Miami | Hard |
| 16.03.22 | 4th round | Grigor Dimitrov | John Isner | 6-3, 7-66 | | match details | Indian Wells | Hard |
| 15.03.22 | 3rd round | John Isner | Diego Sebastian Schwartzman | 7-5, 6-3 | | match details | ||
| 13.03.22 | 2nd round | John Isner | Sam Querrey | 7-66, 7-62 | | match details | ||
| 23.02.22 | 2nd round | Cameron Norrie | John Isner | 6-72, 6-3, 6-4 | | match details | Acapulco | Hard |
| 21.02.22 | 1st round | John Isner | Fernando Verdasco | 7-5, 6-74, 7-63 | | match details | ||
| 18.01.22 | 1st round | Maxime Cressy | John Isner | 7-62, 7-5, 6-74, 6-74, 6-4 | | match details | Melbourne | Hard |
| 12.01.22 | 2nd round | Thanasi Kokkinakis | John Isner | 6-75, 7-65, 7-64 | | match details | Adelaide | Hard |
| 06.01.22 | Daniel Evans | John Isner | 6-4, 7-63 | | match details | Sydney | Hard | |
| 04.01.22 | Jan-Lennard Struff | John Isner | 7-67, 4-6, 7-5 | | match details | |||
| 02.01.22 | John Isner | Brayden Schnur | 6-1, 6-3 | | match details | |||
| 12.10.21 | 3rd round | Jannik Sinner | John Isner | John Isner - walk over | | match details | Indian Wells | Hard |
| 10.10.21 | 2nd round | John Isner | Yoshihito Nishioka | 6-3, 6-4 | | match details | ||
| 30.08.21 | 1st round | Brandon Nakashima | John Isner | 7-67, 7-66, 6-3 | | match details | New York | Hard |
| 19.08.21 | 3rd round | Benoit Paire | John Isner | 7-61, 6-72, 6-1 | | match details | Cincinnati | Hard |
| 18.08.21 | 2nd round | John Isner | Jannik Sinner | 5-7, 7-64, 6-4 | | match details | ||
| 17.08.21 | 1st round | John Isner | Cameron Norrie | 4-6, 7-65, 6-4 | | match details | ||
| 14.08.21 | 1/2 | Daniil Medvedev | John Isner | 6-2, 6-2 | | match details |  Toronto | Hard |
| 13.08.21 | 1/4 | John Isner | Gael Monfils | 7-65, 6-4 | | match details | ||
| 12.08.21 | 3rd round | John Isner | Andrey Rublev | 7-5, 7-65 | | match details | ||
| 11.08.21 | 2nd round | John Isner | Cristian Garin | 4-6, 6-3, 6-4 | | match details | ||
| 10.08.21 | 1st round | John Isner | Alejandro Davidovich Fokina | 6-4, 6-1 | | match details | ||
| 01.08.21 | fin | John Isner | Brandon Nakashima | 7-68, 7-5 | | match details | Atlanta | Hard |
| 31.07.21 | 1/2 | John Isner | Taylor Harry Fritz | 7-64, 5-7, 6-3 | | match details | ||
| 30.07.21 | 1/4 | John Isner | Christopher O'Connell | 7-65, 6-73, 6-4 | | match details | ||
| 29.07.21 | 2nd round | John Isner | Jack Sock | 7-66, 6-4 | | match details | ||
| 27.07.21 | 1st round | John Isner | Jeff Wolf | 6-4, 6-73, 6-4 | | match details | ||
| 23.07.21 | 1/2 | Brandon Nakashima | John Isner | 7-5, 6-4 | | match details | Los Cabos | Hard |
| 22.07.21 | 1/4 | John Isner | Alex Bolt | 6-3, 6-4 | | match details | ||
| 21.07.21 | 2nd round | John Isner | Evgeny Donskoy | 7-5, 3-6, 7-65 | | match details | ||
| 30.03.21 | 4th round | Roberto Bautista Agut | John Isner | 6-3, 4-6, 7-67 | | match details | Miami | Hard |
| 28.03.21 | 3rd round | John Isner | Felix Auger Aliassime | 7-65, 7-65 | | match details | ||
| 26.03.21 | 2nd round | John Isner | Mackenzie Mcdonald | 2-6, 6-3, 7-5 | | match details | ||
| 17.03.21 | 2nd round | Stefanos Tsitsipas | John Isner | 6-3, 6-2 | | match details | Acapulco | Hard |
| 15.03.21 | 1st round | John Isner | Salvatore Caruso | 6-4, 6-3 | | match details | ||
| 11.01.21 | 1/4 | Sebastian Korda | John Isner | 6-3, 4-6, 6-3 | | match details | Delray Beach | Hard |
| 09.01.21 | 2nd round | John Isner | Thiago Moura Monteiro | 6-4, 7-64 | | match details | ||
| 31.08.20 | 1st round | Steve Johnson | John Isner | 6-75, 6-3, 6-75, 6-3, 7-63 | | match details | New York | Hard |
| 25.08.20 | 3rd round | Stefanos Tsitsipas | John Isner | 7-62, 7-64 | | match details | New York | Hard |
| 24.08.20 | 2nd round | John Isner | John Millman | 4-6, 7-63, 7-65 | | match details | ||
| 23.08.20 | 1st round | John Isner | Hubert Hurkacz | 7-5, 6-4 | | match details | ||
| 28.02.20 | 1/2 | Taylor Harry Fritz | John Isner | 2-6, 7-5, 6-3 | | match details | Acapulco | Hard |
| 27.02.20 | 1/4 | John Isner | Tommy Paul | 7-63, 3-6, 6-2 | | match details | ||
| 26.02.20 | 2nd round | John Isner | Marcos Giron | 6-3, 7-64 | | match details | ||
| 25.02.20 | 1st round | John Isner | Mischa Zverev | 6-3, 7-64 | | match details | ||
| 25.01.20 | 3rd round | Stan Wawrinka | John Isner | 6-4, 4-1, John Isner - retired | | match details | Melbourne | Hard |
| 23.01.20 | 2nd round | John Isner | Alejandro Tabilo | 6-4, 6-3, 6-3 | | match details | ||
| 21.01.20 | 1st round | John Isner | Thiago Moura Monteiro | 6-75, 7-64, 7-67, 7-65 | | match details | ||
| 17.01.20 | 1/2 | Ugo Humbert | John Isner | 7-65, 6-4 | | match details | Auckland | Hard |
| 16.01.20 | 1/4 | John Isner | Kyle Edmund | 7-65, 7-65 | | match details | ||
| 15.01.20 | 2nd round | John Isner | Tennys Sandgren | 7-63, 6-71, 6-3 | | match details | ||
| 07.01.20 | Fabio Fognini | John Isner | 6-4, 7-65 | | match details | Brisbane Perth | Hard | |
| 05.01.20 | Daniil Medvedev | John Isner | 6-3, 6-1 | | match details | |||
| 03.01.20 | Casper Ruud | John Isner | 6-73, 7-610, 7-5 | | match details | |||
| 10.10.19 | 3rd round | Novak Djokovic | John Isner | 7-5, 6-3 | | match details |  Shanghai | Hard |
| 09.10.19 | 2nd round | John Isner | Lucas Pouille | 7-5, 6-3 | | match details | ||
| 08.10.19 | 1st round | John Isner | Alex De Minaur | 7-61, 6-4 | | match details | ||
| 04.10.19 | 1/4 | Stefanos Tsitsipas | John Isner | 7-63, 6-3 | | match details | Beijing | Hard |
| 03.10.19 | 2nd round | John Isner | Daniel Evans | 7-63, 7-5 | | match details | ||
| 01.10.19 | 1st round | John Isner | Gael Monfils | 6-4, 6-75, 6-3 | | match details | ||
| 26.09.19 | 2nd round | Egor Gerasimov | John Isner | 6-711, 7-65, 7-64 | | match details | Chengdu | Hard |
| 31.08.19 | 3rd round | Marin Cilic | John Isner | 7-5, 3-6, 7-66, 6-4 | | match details | New York | Hard |
| 29.08.19 | 2nd round | John Isner | Jan-Lennard Struff | 6-3, 7-64, 7-65 | | match details | ||
| 27.08.19 | 1st round | John Isner | Guillermo Garcia-Lopez | 6-3, 6-4, 6-4 | | match details | ||
| 13.08.19 | 2nd round | Pablo Carreno-Busta | John Isner | 6-4, 6-71, 7-66 | | match details | Cincinnati | Hard |
| 11.08.19 | 1st round | John Isner | Dusan Lajovic | 7-63, 1-6, 7-5 | | match details | ||
| 07.08.19 | 2nd round | Cristian Garin | John Isner | 6-3, 6-4 | | match details | Montreal | Hard |
| 06.08.19 | 1st round | John Isner | Jordan Thompson | 3-6, 6-3, 7-66 | | match details | ||
| 01.08.19 | 3rd round | Benoit Paire | John Isner | 7-63, 6-3 | | match details | Washington | Hard |
| 31.07.19 | 2nd round | John Isner | Hubert Hurkacz | 6-4, 6-4 | | match details | ||
| 24.07.19 | 2nd round | Reilly Opelka | John Isner | 7-62, 6-75, 7-65 | | match details | Atlanta | Hard |
| 31.03.19 | fin | Roger Federer | John Isner | 6-1, 6-4 | | match details | Miami | Hard |
| 29.03.19 | 1/2 | John Isner | Felix Auger Aliassime | 7-63, 7-64 | | match details | ||
| 27.03.19 | 1/4 | John Isner | Roberto Bautista Agut | 7-61, 7-65 | | match details | ||
| 26.03.19 | 4th round | John Isner | Kyle Edmund | 7-65, 7-63 | | match details | ||
| 24.03.19 | 3rd round | John Isner | Albert Ramos-Vinolas | 7-5, 7-66 | | match details | ||
| 22.03.19 | 2nd round | John Isner | Lorenzo Sonego | 7-62, 7-67 | | match details | ||
| 13.03.19 | 4th round | Karen Khachanov | John Isner | 6-4, 7-61 | | match details | Indian Wells | Hard |
| 12.03.19 | 3rd round | John Isner | Guido Pella | 6-3, 6-4 | | match details | ||
| 10.03.19 | 2nd round | John Isner | Alexei Popyrin | 6-0, 6-2 | | match details | ||
| 01.03.19 | 1/2 | Nick Kyrgios | John Isner | 7-5, 5-7, 7-67 | | match details | Acapulco | Hard |
| 28.02.19 | 1/4 | John Isner | John Millman | 7-62, 6-74, 7-64 | | match details | ||
| 27.02.19 | 2nd round | John Isner | Sam Querrey | 6-4, 6-4 | | match details | ||
| 26.02.19 | 1st round | John Isner | Adrian Mannarino | 6-3, 4-6, 6-3 | | match details | ||
| 23.02.19 | 1/2 | Daniel Evans | John Isner | 3-6, 6-2, 6-3 | | match details | Delray Beach | Hard |
| 22.02.19 | 1/4 | John Isner | Adrian Mannarino | 7-62, 6-4 | | match details | ||
| 20.02.19 | 2nd round | John Isner | Lukas Lacko | 6-4, 6-3 | | match details | ||
| 19.02.19 | 1st round | John Isner | Peter Polansky | 6-3, 7-64 | | match details | ||
| 14.01.19 | 1st round | Reilly Opelka | John Isner | 7-64, 7-66, 6-74, 7-65 | | match details | Melbourne | Hard |
| 09.01.19 | 2nd round | Taylor Harry Fritz | John Isner | 7-63, 7-65 | | match details | Auckland | Hard |
| 04.09.18 | 1/4 | Juan Martin Del Potro | John Isner | 6-75, 6-3, 7-64, 6-2 | | match details | New York | Hard |
| 02.09.18 | 4th round | John Isner | Milos Raonic | 3-6, 6-3, 6-4, 3-6, 6-2 | | match details | ||
| 31.08.18 | 3rd round | John Isner | Dusan Lajovic | 7-68, 6-76, 6-3, 7-5 | | match details | ||
| 29.08.18 | 2nd round | John Isner | Nicolas Jarry | 6-77, 6-4, 3-6, 7-62, 6-4 | | match details | ||
| 27.08.18 | 1st round | John Isner | Bradley Klahn | 7-63, 6-3, 6-4 | | match details | ||
| 13.08.18 | 1st round | Sam Querrey | John Isner | 6-4, 6-75, 7-65 | | match details | Cincinnati | Hard |
| 09.08.18 | 3rd round | Karen Khachanov | John Isner | 7-65, 7-61 | | match details | Toronto | Hard |
| 08.08.18 | 2nd round | John Isner | Pierre-Hugues Herbert | 7-63, 6-2 | | match details | ||
| 02.08.18 | 2nd round | Noah Rubin | John Isner | 6-4, 7-66 | | match details | Washington | Hard |
| 29.07.18 | fin | John Isner | Ryan Harrison | 5-7, 6-3, 6-4 | | match details | Atlanta | Hard |
| 28.07.18 | 1/2 | John Isner | Matthew Ebden | 6-4, 6-76, 6-1 | | match details | ||
| 27.07.18 | 1/4 | John Isner | Mischa Zverev | 7-5, 4-6, 6-1 | | match details | ||
| 25.07.18 | 2nd round | John Isner | Alex De Minaur | 6-3, 6-2 | | match details | ||
| 01.04.18 | fin | John Isner | Alexander Zverev | 6-74, 6-4, 6-4 | | match details | Miami | Hard |
| 30.03.18 | 1/2 | John Isner | Juan Martin Del Potro | 6-1, 7-62 | | match details | ||
| 28.03.18 | 1/4 | John Isner | Hyeon Chung | 6-1, 6-4 | | match details | ||
| 27.03.18 | 4th round | John Isner | Marin Cilic | 7-60, 6-3 | | match details | ||
| 25.03.18 | 3rd round | John Isner | Mikhail Youzhny | 6-4, 6-3 | | match details | ||
| 23.03.18 | 2nd round | John Isner | Jiri Vesely | 7-63, 1-6, 6-3 | | match details | ||
| 11.03.18 | 2nd round | Gael Monfils | John Isner | 6-75, 7-63, 7-5 | | match details | Indian Wells | Hard |
| 26.02.18 | 1st round | Ryan Harrison | John Isner | 6-3, 7-65 | | match details | Acapulco | Hard |
| 21.02.18 | 2nd round | Peter Gojowczyk | John Isner | 7-63, 6-74, 7-65 | | match details | Delray Beach | Hard |
| 20.02.18 | 1st round | John Isner | Radu Albot | 5-7, 6-3, 6-4 | | match details | ||
| 15.01.18 | 1st round | Matthew Ebden | John Isner | 6-4, 3-6, 6-3, 6-3 | | match details | Melbourne | Hard |
| 10.01.18 | 2nd round | Hyeon Chung | John Isner | 7-63, 5-7, 6-2 | | match details | Auckland | Hard |
| 12.10.17 | 3rd round | Viktor Troicki | John Isner | 6-4, 7-64 | | match details | Shanghai | Hard |
| 11.10.17 | 2nd round | John Isner | Stefanos Tsitsipas | 7-62, 7-69 | | match details | ||
| 10.10.17 | 1st round | John Isner | Dusan Lajovic | 4-6, 7-65, 7-66 | | match details | ||
| 06.10.17 | 1/4 | Rafael Nadal | John Isner | 6-4, 7-60 | | match details | Beijing | Hard |
| 05.10.17 | 2nd round | John Isner | Leonardo Mayer | 6-0, 6-3 | | match details | ||
| 03.10.17 | 1st round | John Isner | Malek Jaziri | 6-2, 6-3 | | match details | ||
| 01.09.17 | 3rd round | Mischa Zverev | John Isner | 6-4, 6-3, 7-65 | | match details | New York | Hard |
| 30.08.17 | 2nd round | John Isner | Hyeon Chung | 6-3, 6-4, 7-5 | | match details | ||
| 28.08.17 | 1st round | John Isner | Pierre-Hugues Herbert | 6-1, 6-3, 4-6, 6-3 | | match details | ||
| 23.08.17 | 3rd round | Borna Coric | John Isner | 7-5, 6-2 | | match details | Winston-Salem | Hard |
| 22.08.17 | 2nd round | John Isner | Andrey Kuznetsov | 2-6, 7-65, 6-3 | | match details | ||
| 19.08.17 | 1/2 | Grigor Dimitrov | John Isner | 7-64, 7-610 | | match details | Cincinnati | Hard |
| 18.08.17 | 1/4 | John Isner | Jared Donaldson | 7-64, 7-5 | | match details | ||
| 17.08.17 | 3rd round | John Isner | Frances Tiafoe | 7-64, 7-5 | | match details | ||
| 15.08.17 | 2nd round | John Isner | Tommy Paul | 6-3, 6-3 | | match details | ||
| 13.08.17 | 1st round | John Isner | Viktor Troicki | 7-63, 6-4 | | match details | ||
| 07.08.17 | 1st round | Juan Martin Del Potro | John Isner | 7-5, 7-5 | | match details | Montreal | Hard |
| 30.07.17 | fin | John Isner | Ryan Harrison | 7-66, 7-67 | | match details | Atlanta | Hard |
| 29.07.17 | 1/2 | John Isner | Gilles Muller | 6-4, 6-2 | | match details | ||
| 28.07.17 | 1/4 | John Isner | Lukas Lacko | 7-5, 6-4 | | match details | ||
| 26.07.17 | 2nd round | John Isner | Vasek Pospisil | 6-3, 6-4 | | match details | ||
| 09.04.17 | John Isner | Samuel Groth | 7-65, 6-3 | | match details | Davis Cup | Hard | |
| 07.04.17 | Nick Kyrgios | John Isner | 7-5, 7-65, 7-65 | | match details | |||
| 27.03.17 | 3rd round | Alexander Zverev | John Isner | 6-75, 7-67, 7-65 | | match details | Miami | Hard |
| 25.03.17 | 2nd round | John Isner | Thomaz Bellucci | 7-5, 7-65 | | match details | ||
| 13.03.17 | 3rd round | Gael Monfils | John Isner | 6-2, 6-4 | | match details | Indian Wells | Hard |
| 11.03.17 | 2nd round | John Isner | Mikhail Kukushkin | 7-60, 7-66 | | match details | ||
| 27.02.17 | 1st round | Steve Johnson | John Isner | 6-4, 6-4 | | match details | Acapulco | Hard |
| 18.01.17 | 2nd round | Mischa Zverev | John Isner | 6-74, 6-74, 6-4, 7-67, 9-7 | | match details | Melbourne | Hard |
| 16.01.17 | 1st round | John Isner | Konstantin Kravchuk | 6-3, 6-4, 6-75, 6-1 | | match details | ||
| 12.01.17 | 1/4 | Steve Johnson | John Isner | 6-3, 5-7, 7-63 | | match details | Auckland | Hard |
| 11.01.17 | 2nd round | John Isner | Malek Jaziri | 6-3, 3-6, 7-66 | | match details | ||
| 10.10.16 | 1st round | Alexander Zverev | John Isner | 6-4, 6-2 | | match details | Shanghai | Hard |
| 02.09.16 | 3rd round | Kyle Edmund | John Isner | 6-4, 3-6, 6-2, 7-65 | | match details | New York | Hard |
| 31.08.16 | 2nd round | John Isner | Steve Darcis | 6-3, 6-4, 6-710, 6-3 | | match details | ||
| 29.08.16 | 1st round | John Isner | Frances Tiafoe | 3-6, 4-6, 7-65, 6-2, 7-63 | | match details | ||
| 17.08.16 | 2nd round | Milos Raonic | John Isner | 7-65, 7-65 | | match details | Cincinnati | Hard |
| 16.08.16 | 1st round | John Isner | Fabio Fognini | 6-3, 6-2 | | match details | ||
| 07.08.16 | fin | Nick Kyrgios | John Isner | 7-63, 7-64 | | match details | Atlanta | Hard |
| 06.08.16 | 1/2 | John Isner | Reilly Opelka | 6-75, 6-4, 6-2 | | match details | ||
| 05.08.16 | 1/4 | John Isner | Taylor Harry Fritz | 7-5, 6-4 | | match details | ||
| 03.08.16 | 2nd round | John Isner | Adrian Mannarino | 6-4, 6-0 | | match details | ||
| 27.07.16 | 2nd round | Ryan Harrison | John Isner | 7-63, 6-74, 6-4 | | match details | Toronto | Hard |
| 25.07.16 | 1st round | John Isner | Dudi Sela | 4-6, 6-3, 6-2 | | match details | ||
| 22.07.16 | 1/4 | Steve Johnson | John Isner | 7-67, 7-615 | | match details | Washington | Hard |
| 21.07.16 | 3rd round | John Isner | Marcos Baghdatis | 7-63, 6-2 | | match details | ||
| 20.07.16 | 2nd round | John Isner | James Duckworth | 6-3, 6-4 | | match details | ||
| 17.07.16 | Marin Cilic | John Isner | 7-69, 6-3, 6-4 | | match details | Davis Cup | Hard | |
| 15.07.16 | John Isner | Borna Coric | 6-4, 6-4, 6-3 | | match details | |||
| 26.03.16 | 2nd round | Tim Smyczek | John Isner | 6-2, 2-6, 7-65 | | match details | Miami | Hard |
| 16.03.16 | 4th round | Kei Nishikori | John Isner | 1-6, 7-62, 7-65 | | match details | Indian Wells | Hard |
| 15.03.16 | 3rd round | John Isner | Adrian Mannarino | 6-4, 7-64 | | match details | ||
| 13.03.16 | 2nd round | John Isner | Andreas Seppi | 7-61, 6-4 | | match details | ||
| 25.01.16 | 4th round | David Ferrer | John Isner | 6-4, 6-4, 7-5 | | match details | Melbourne | Hard |
| 23.01.16 | 3rd round | John Isner | Feliciano Lopez | 6-78, 7-65, 6-2, 6-4 | | match details | ||
| 21.01.16 | 2nd round | John Isner | Marcel Granollers | 6-3, 7-66, 7-62 | | match details | ||
| 19.01.16 | 1st round | John Isner | Jerzy Janowicz | 6-3, 7-67, 6-3 | | match details | ||
| 14.01.16 | 1/4 | Roberto Bautista Agut | John Isner | 7-5, 2-6, 6-3 | | match details | Auckland | Hard |
| 13.01.16 | 2nd round | John Isner | Sam Querrey | 7-68, 6-74, 6-4 | | match details | ||
| 15.10.15 | 3rd round | Andy Murray | John Isner | 6-74, 6-4, 6-4 | | match details | Shanghai | Hard |
| 14.10.15 | 2nd round | John Isner | David Goffin | 6-3, 7-65 | | match details | ||
| 12.10.15 | 1st round | John Isner | Adrian Mannarino | 6-1, 6-2 | | match details | ||
| 09.10.15 | 1/4 | Novak Djokovic | John Isner | 6-2, 6-2 | | match details | Beijing | Hard |
| 08.10.15 | 2nd round | John Isner | John Millman | 4-6, 7-65, 6-4 | | match details | ||
| 06.10.15 | 1st round | John Isner | Dominic Thiem | 7-5, 6-1 | | match details | ||
| 07.09.15 | 4th round | Roger Federer | John Isner | 7-60, 7-66, 7-5 | | match details | New York | Hard |
| 05.09.15 | 3rd round | John Isner | Jiri Vesely | 6-3, 6-4, Jiri Vesely - retired | | match details | ||
| 03.09.15 | 2nd round | John Isner | Mikhail Youzhny | 6-3, 6-4, 6-4 | | match details | ||
| 01.09.15 | 1st round | John Isner | Malek Jaziri | 6-2, 6-3, 6-4 | | match details | ||
| 18.08.15 | 1st round | Sam Querrey | John Isner | 6-3, 7-63 | | match details | Cincinnati | Hard |
| 14.08.15 | 1/4 | Jeremy Chardy | John Isner | 6-79, 7-613, 7-64 | | match details | Montreal | Hard |
| 13.08.15 | 3rd round | John Isner | Nick Kyrgios | 7-5, 6-3 | | match details | ||
| 12.08.15 | 2nd round | John Isner | Vasek Pospisil | 7-61, 4-6, 6-3 | | match details | ||
| 11.08.15 | 1st round | John Isner | Benjamin Becker | 6-4, 6-76, 6-3 | | match details | ||
| 09.08.15 | fin | Kei Nishikori | John Isner | 4-6, 6-4, 6-4 | | match details | Washington | Hard |
| 08.08.15 | 1/2 | John Isner | Steve Johnson | 6-3, 3-6, 7-69 | | match details | ||
| 07.08.15 | 1/4 | John Isner | Ricardas Berankis | 6-3, 5-7, 6-3 | | match details | ||
| 06.08.15 | 3rd round | John Isner | Vasek Pospisil | 6-4, 7-66 | | match details | ||
| 05.08.15 | 2nd round | John Isner | Victor Estrella | 6-3, 7-65 | | match details | ||
| 02.08.15 | fin | John Isner | Marcos Baghdatis | 6-3, 6-3 | | match details | Atlanta | Hard |
| 01.08.15 | 1/2 | John Isner | Denis Kudla | 4-6, 6-2, 7-5 | | match details | ||
| 31.07.15 | 1/4 | John Isner | Ricardas Berankis | 7-65, 6-4 | | match details | ||
| 30.07.15 | 2nd round | John Isner | Radek Stepanek | 7-63, 7-67 | | match details | ||
| 03.04.15 | 1/2 | Novak Djokovic | John Isner | 7-63, 6-2 | | match details | Miami | Hard |
| 02.04.15 | 1/4 | John Isner | Kei Nishikori | 6-4, 6-3 | | match details | ||
| 31.03.15 | 4th round | John Isner | Milos Raonic | 6-73, 7-66, 7-65 | | match details | ||
| 30.03.15 | 3rd round | John Isner | Grigor Dimitrov | 7-62, 6-2 | | match details | ||
| 28.03.15 | 2nd round | John Isner | Andrey Rublev | 6-3, 6-4 | | match details | ||
| 18.03.15 | 4th round | Novak Djokovic | John Isner | 6-4, 7-65 | | match details | Indian Wells | Hard |
| 16.03.15 | 3rd round | John Isner | Kevin Anderson | 7-66, 6-2 | | match details | ||
| 14.03.15 | 2nd round | John Isner | Jurgen Melzer | 6-3, 6-4 | | match details | ||
| 17.02.15 | 1st round | Marinko Matosevic | John Isner | 6-4, 6-4 | | match details | Delray Beach | Hard |
| 24.01.15 | 3rd round | Gilles Muller | John Isner | 7-64, 7-66, 6-4 | | match details | Melbourne | Hard |
| 22.01.15 | 2nd round | John Isner | Andreas Haider-Maurer | 6-4, 7-64, 4-6, 6-4 | | match details | ||
| 20.01.15 | 1st round | John Isner | Jimmy Wang | 7-65, 6-4, 6-4 | | match details | ||
| 09.10.14 | 3rd round | Feliciano Lopez | John Isner | 6-3, 6-4 | | match details | Shanghai | Hard |
| 08.10.14 | 2nd round | John Isner | Steve Johnson | 7-66, 7-67 | | match details | ||
| 06.10.14 | 1st round | John Isner | Pablo Andujar | 7-65, 1-6, 6-3 | | match details | ||
| 03.10.14 | 1/4 | Tomas Berdych | John Isner | 6-1, 6-4 | | match details | Beijing | Hard |
| 01.10.14 | 2nd round | John Isner | Tommy Robredo | 3-6, 7-5, 7-64 | | match details | ||
| 30.09.14 | 1st round | John Isner | Santiago Giraldo | 6-1, 6-3 | | match details | ||
| 30.08.14 | 3rd round | Philipp Kohlschreiber | John Isner | 7-64, 4-6, 7-62, 7-64 | | match details | New York | Hard |
| 28.08.14 | 2nd round | John Isner | Jan-Lennard Struff | 7-65, 6-4, 6-2 | | match details | ||
| 26.08.14 | 1st round | John Isner | Marcos Giron | 7-65, 6-2, 7-62 | | match details | ||
| 21.08.14 | 1/4 | Lukas Rosol | John Isner | John Isner - walk over | | match details | Winston-Salem | Hard |
| 20.08.14 | 3rd round | John Isner | Mikhail Kukushkin | 6-1, 7-63 | | match details | ||
| 19.08.14 | 2nd round | John Isner | Bradley Klahn | 7-65, 6-2 | | match details | ||
| 14.08.14 | 3rd round | Andy Murray | John Isner | 6-73, 6-4, 7-62 | | match details | Cincinnati | Hard |
| 13.08.14 | 2nd round | John Isner | Marinko Matosevic | 6-3, 7-61 | | match details | ||
| 11.08.14 | 1st round | John Isner | Kevin Anderson | 6-3, 6-4 | | match details | ||
| 04.08.14 | 1st round | Ivan Dodig | John Isner | 6-4, 6-74, 6-3 | | match details | Toronto | Hard |
| 30.07.14 | 2nd round | Steve Johnson | John Isner | 6-75, 6-3, 7-66 | | match details | Washington | Hard |
| 27.07.14 | fin | John Isner | Dudi Sela | 6-3, 6-4 | | match details | Atlanta | Hard |
| 26.07.14 | 1/2 | John Isner | Jack Sock | 7-5, 6-4 | | match details | ||
| 25.07.14 | 1/4 | John Isner | Marinko Matosevic | 7-68, 6-4 | | match details | ||
| 24.07.14 | 2nd round | John Isner | Robby Ginepri | 4-6, 7-65, 7-5 | | match details | ||
| 25.03.14 | 4th round | Tomas Berdych | John Isner | 6-3, 7-5 | | match details | Miami | Hard |
| 24.03.14 | 3rd round | John Isner | Nicolas Almagro | 7-5, 6-3 | | match details | ||
| 22.03.14 | 2nd round | John Isner | Donald Young | 6-75, 6-3, 6-4 | | match details | ||
| 15.03.14 | 1/2 | Novak Djokovic | John Isner | 7-5, 6-72, 6-1 | | match details | Indian Wells | Hard |
| 14.03.14 | 1/4 | John Isner | Ernests Gulbis | 7-64, 7-63 | | match details | ||
| 12.03.14 | 4th round | John Isner | Fernando Verdasco | 7-63, 3-6, 6-3 | | match details | ||
| 11.03.14 | 3rd round | John Isner | Yen-Hsun Lu | 6-4, 6-3 | | match details | ||
| 09.03.14 | 2nd round | John Isner | Nikolay Davydenko | 7-65, 6-3 | | match details | ||
| 25.02.14 | 1st round | Ivo Karlovic | John Isner | 7-64, 7-65 | | match details | Acapulco | Hard |
| 22.02.14 | 1/2 | Marin Cilic | John Isner | 7-65, 6-3 | | match details | Delray Beach | Hard |
| 21.02.14 | 1/4 | John Isner | Rhyne Williams | 4-6, 6-3, 6-2 | | match details | ||
| 20.02.14 | 2nd round | John Isner | Dudi Sela | 3-6, 6-1, 7-65 | | match details | ||
| 18.02.14 | 1st round | John Isner | Michael Russell | 4-6, 7-63, 6-4 | | match details | ||
| 14.01.14 | 1st round | Martin Klizan | John Isner | 6-2, 7-66, John Isner - retired | | match details | Melbourne | Hard |
| 11.01.14 | fin | John Isner | Yen-Hsun Lu | 7-64, 7-67 | | match details | Auckland | Hard |
| 10.01.14 | 1/2 | John Isner | Roberto Bautista Agut | 3-6, 7-62, 6-4 | | match details | ||
| 09.01.14 | 1/4 | John Isner | Philipp Kohlschreiber | 6-74, 7-64, 7-65 | | match details | ||
| 08.01.14 | 2nd round | John Isner | Lukas Lacko | 7-61, 3-6, 6-2 | | match details | ||
| 03.01.14 | Radek Stepanek | John Isner | John Isner - walk over | | match details | Perth | Hard | |
| 01.01.14 | Jo-Wilfried Tsonga | John Isner | 7-61, 6-3 | | match details | |||
| 30.12.13 | John Isner | Daniel Munoz-De La Nava | 6-3, 6-4 | | match details | |||
| 09.10.13 | 2nd round | Carlos Berlocq | John Isner | 6-4, 7-64 | | match details | Shanghai | Hard |
| 07.10.13 | 1st round | John Isner | Santiago Giraldo | 4-6, 7-5, 7-5 | | match details | ||
| 04.10.13 | 1/4 | Tomas Berdych | John Isner | 7-5, 6-2 | | match details | Beijing | Hard |
| 02.10.13 | 2nd round | John Isner | Roberto Bautista Agut | 6-2, 6-73, 6-4 | | match details | ||
| 01.10.13 | 1st round | John Isner | Di Wu | 5-7, 7-64, 6-3 | | match details | ||
| 31.08.13 | 3rd round | Philipp Kohlschreiber | John Isner | 6-4, 3-6, 7-5, 7-65 | | match details | New York | Hard |
| 29.08.13 | 2nd round | John Isner | Gael Monfils | 7-5, 6-2, 4-6, 7-64 | | match details | ||
| 27.08.13 | 1st round | John Isner | Filippo Volandri | 6-0, 6-2, 6-3 | | match details | ||
| 18.08.13 | fin | Rafael Nadal | John Isner | 7-68, 7-63 | | match details | Cincinnati | Hard |
| 17.08.13 | 1/2 | John Isner | Juan Martin Del Potro | 6-75, 7-69, 6-3 | | match details | ||
| 16.08.13 | 1/4 | John Isner | Novak Djokovic | 7-65, 3-6, 7-5 | | match details | ||
| 15.08.13 | 3rd round | John Isner | Milos Raonic | 7-65, 6-4 | | match details | ||
| 14.08.13 | 2nd round | John Isner | Richard Gasquet | 7-66, 6-2 | | match details | ||
| 13.08.13 | 1st round | John Isner | Florian Mayer | 6-3, 6-4 | | match details | ||
| 06.08.13 | 1st round | Vasek Pospisil | John Isner | 5-7, 7-65, 7-64 | | match details | Montreal | Hard |
| 04.08.13 | fin | Juan Martin Del Potro | John Isner | 3-6, 6-1, 6-2 | | match details | Washington | Hard |
| 03.08.13 | 1/2 | John Isner | Dmitry Tursunov | 6-77, 6-3, 6-4 | | match details | ||
| 02.08.13 | 1/4 | John Isner | Marcos Baghdatis | 6-75, 6-4, 6-4 | | match details | ||
| 01.08.13 | 3rd round | John Isner | Somdev Devvarman | 7-5, 7-5 | | match details | ||
| 31.07.13 | 2nd round | John Isner | Alex Kuznetsov | 7-62, 7-64 | | match details | ||
| 28.07.13 | fin | John Isner | Kevin Anderson | 6-73, 7-62, 7-62 | | match details | Atlanta | Hard |
| 27.07.13 | 1/2 | John Isner | Lleyton Hewitt | 6-4, 4-6, 7-65 | | match details | ||
| 26.07.13 | 1/4 | John Isner | James Blake | 7-61, 7-65 | | match details | ||
| 25.07.13 | 2nd round | John Isner | Christian Harrison | 7-69, 4-6, 7-5 | | match details | ||
| 25.03.13 | 3rd round | Marin Cilic | John Isner | 6-3, 7-63 | | match details | Miami | Hard |
| 23.03.13 | 2nd round | John Isner | Ivan Dodig | 4-6, 7-5, 7-65 | | match details | ||
| 09.03.13 | 2nd round | Lleyton Hewitt | John Isner | 6-76, 6-3, 6-4 | | match details | Indian Wells | Hard |
| 02.03.13 | 1/2 | Edouard Roger-Vasselin | John Isner | 6-4, 4-6, 6-4 | | match details | Delray Beach | Hard |
| 01.03.13 | 1/4 | John Isner | Kevin Anderson | 6-2, 7-61 | | match details | ||
| 28.02.13 | 2nd round | John Isner | Go Soeda | 7-62, 6-2 | | match details | ||
| 26.02.13 | 1st round | John Isner | Jesse Levine | 7-63, 5-7, 6-4 | | match details | ||
| 09.01.13 | 2nd round | Ryan Harrison | John Isner | 6-4, 6-4 | | match details | Sydney | Hard |
| 01.01.13 | Jo-Wilfried Tsonga | John Isner | 6-3, 6-2 | | match details | Perth | Hard | |
| 30.12.12 | Kevin Anderson | John Isner | 7-60, 7-65 | | match details | |||
| 11.10.12 | 3rd round | Radek Stepanek | John Isner | 6-4, 6-75, 6-3 | | match details | Shanghai | Hard |
| 09.10.12 | 2nd round | John Isner | Kevin Anderson | 7-63, 6-78, 7-67 | | match details | ||
| 02.09.12 | 3rd round | Philipp Kohlschreiber | John Isner | 6-4, 3-6, 4-6, 6-3, 6-4 | | match details | New York | Hard |
| 31.08.12 | 2nd round | John Isner | Jarkko Nieminen | 6-3, 6-75, 6-4, 6-3 | | match details | ||
| 29.08.12 | 1st round | John Isner | Xavier Malisse | 6-3, 7-65, 5-7, 7-69 | | match details | ||
| 25.08.12 | fin | John Isner | Tomas Berdych | 3-6, 6-4, 7-69 | | match details | Winston-Salem | Hard |
| 24.08.12 | 1/2 | John Isner | Jo-Wilfried Tsonga | 6-4, 3-6, 7-63 | | match details | ||
| 23.08.12 | 1/4 | John Isner | David Goffin | 7-65, 6-3 | | match details | ||
| 22.08.12 | 3rd round | John Isner | Jurgen Melzer | 6-4, 6-3 | | match details | ||
| 21.08.12 | 2nd round | John Isner | Martin Klizan | 4-6, 6-3, 7-5 | | match details | ||
| 11.08.12 | 1/2 | Richard Gasquet | John Isner | 7-63, 6-3 | | match details | Toronto | Hard |
| 10.08.12 | 3rd round | John Isner | Philipp Kohlschreiber | 6-73, 6-4, 6-4 | | match details | ||
| 10.08.12 | 1/4 | John Isner | Milos Raonic | 7-69, 6-4 | | match details | ||
| 07.08.12 | 2nd round | John Isner | Pablo Andujar | 7-65, 7-5 | | match details | ||
| 21.07.12 | 1/2 | Andy Roddick | John Isner | 6-4, 6-75, 6-4 | | match details | Atlanta | Hard |
| 20.07.12 | 1/4 | John Isner | Jack Sock | 7-67, 6-4 | | match details | ||
| 19.07.12 | 2nd round | John Isner | Ruben Bemelmans | 4-6, 6-3, 6-4 | | match details | ||
| 25.03.12 | 3rd round | Florian Mayer | John Isner | 6-4, 6-2 | | match details | Miami | Hard |
| 23.03.12 | 2nd round | John Isner | Nikolay Davydenko | 2-6, 6-3, 6-4 | | match details | ||
| 18.03.12 | fin | Roger Federer | John Isner | 7-67, 6-3 | | match details | Indian Wells | Hard |
| 17.03.12 | 1/2 | John Isner | Novak Djokovic | 7-67, 3-6, 7-65 | | match details | ||
| 15.03.12 | 1/4 | John Isner | Gilles Simon | 6-3, 1-6, 7-5 | | match details | ||
| 14.03.12 | 4th round | John Isner | Matthew Ebden | 6-4, 7-5 | | match details | ||
| 12.03.12 | 3rd round | John Isner | Juan Monaco | 7-5, 7-5 | | match details | ||
| 10.03.12 | 2nd round | John Isner | Frederico Gil | 7-5, 6-3 | | match details | ||
| 03.03.12 | 1/2 | Kevin Anderson | John Isner | 7-5, 7-64 | | match details | Delray Beach | Hard |
| 02.03.12 | 1/4 | John Isner | Bernard Tomic | 6-3, 6-2 | | match details | ||
| 29.02.12 | 2nd round | John Isner | Ryan Sweeting | 6-3, 6-4 | | match details | ||
| 28.02.12 | 1st round | John Isner | Jesse Levine | 6-4, 7-615 | | match details | ||
| 20.01.12 | 3rd round | Feliciano Lopez | John Isner | 6-3, 6-73, 6-4, 6-70, 6-1 | | match details | Melbourne | Hard |
| 18.01.12 | 2nd round | John Isner | David Nalbandian | 4-6, 6-3, 2-6, 7-65, 10-8 | | match details | ||
| 16.01.12 | 1st round | John Isner | Benjamin Mitchell | 6-4, 6-4, 7-61 | | match details | ||
| 11.01.12 | 2nd round | Bobby Reynolds | John Isner | 3-6, 6-4, 6-3 | | match details | Sydney | Hard |
| 09.09.11 | 1/4 | Andy Murray | John Isner | 7-5, 6-4, 3-6, 7-62 | | match details | New York | Hard |
| 08.09.11 | 4th round | John Isner | Gilles Simon | 7-62, 3-6, 7-62, 7-64 | | match details | ||
| 04.09.11 | 3rd round | John Isner | Alex Jr. Bogomolov | 7-69, 6-4, 6-4 | | match details | ||
| 02.09.11 | 2nd round | John Isner | Robby Ginepri | 6-4, 6-3, 6-4 | | match details | ||
| 31.08.11 | 1st round | John Isner | Marcos Baghdatis | 7-62, 7-611, 2-6, 6-4 | | match details | ||
| 27.08.11 | fin | John Isner | Julien Benneteau | 4-6, 6-3, 6-4 | | match details | Winston Salem | Hard |
| 26.08.11 | 1/2 | John Isner | Andy Roddick | 7-67, 6-4 | | match details | ||
| 25.08.11 | 1/4 | John Isner | Marcos Baghdatis | 1-6, 6-3, 6-4 | | match details | ||
| 24.08.11 | 3rd round | John Isner | Jarkko Nieminen | 7-64, 6-2 | | match details | ||
| 23.08.11 | 2nd round | John Isner | Dudi Sela | 7-63, 6-2 | | match details | ||
| 16.08.11 | 1st round | Radek Stepanek | John Isner | 7-5, 5-7, 7-64 | | match details | Cincinnati | Hard |
| 10.08.11 | 1st round | John Isner | Marcos Baghdatis | 6-3, 6-4 | | match details | Montreal | Hard |
| 10.08.11 | 2nd round | Viktor Troicki | John Isner | 6-4, 3-6, 6-2 | | match details | ||
| 06.08.11 | 1/2 | Gael Monfils | John Isner | 6-4, 3-6, 7-66 | | match details | Washington | Hard |
| 05.08.11 | 1/4 | John Isner | Viktor Troicki | 7-65, 3-6, 6-1 | | match details | ||
| 04.08.11 | 3rd round | John Isner | James Blake | 7-60, 1-6, 7-64 | | match details | ||
| 02.08.11 | 2nd round | John Isner | Tobias Kamke | 6-1, 6-3 | | match details | ||
| 24.07.11 | fin | Mardy Fish | John Isner | 3-6, 7-66, 6-2 | | match details | Atlanta | Hard |
| 23.07.11 | 1/2 | John Isner | Gilles Muller | 7-5, 6-73, 6-1 | | match details | ||
| 22.07.11 | 1/4 | John Isner | Yen-Hsun Lu | 6-1, 6-2 | | match details | ||
| 20.07.11 | 2nd round | John Isner | James Blake | 7-68, 6-73, 7-5 | | match details | ||
| 29.03.11 | 4th round | Kevin Anderson | John Isner | 6-3, 7-64 | | match details | Miami | Hard |
| 27.03.11 | 3rd round | John Isner | Alex Jr. Bogomolov | 6-2, 7-64 | | match details | ||
| 25.03.11 | 2nd round | John Isner | Igor Andreev | 6-4, 5-7, 7-62 | | match details | ||
| 15.03.11 | 3rd round | Andy Roddick | John Isner | 7-5, 6-2 | | match details | Indian Wells | Hard |
| 13.03.11 | 2nd round | John Isner | Ricardo Mello | 6-3, 7-62 | | match details | ||
| 21.02.11 | 1st round | Teimuraz Gabashvili | John Isner | 6-4, 5-7, 7-613 | | match details | Delray Beach | Hard |
| 22.01.11 | 3rd round | Marin Cilic | John Isner | 4-6, 6-2, 6-75, 7-62, 9-7 | | match details | Melbourne | Hard |
| 20.01.11 | 2nd round | John Isner | Radek Stepanek | 4-6, 6-4, 6-2, 6-1 | | match details | ||
| 18.01.11 | 1st round | John Isner | Florent Serra | 6-3, 7-68, 6-3 | | match details | ||
| 13.01.11 | 1/4 | David Nalbandian | John Isner | 6-4, 7-63 | | match details | Auckland | Hard |
| 12.01.11 | 2nd round | John Isner | Robin Haase | 3-6, 7-64, 7-5 | | match details | ||
| 13.10.10 | 2nd round | Roger Federer | John Isner | 6-3, 6-4 | | match details | Shanghai | Hard |
| 12.10.10 | 1st round | John Isner | Lukasz Kubot | 4-6, 7-69, 7-67 | | match details | ||
| 09.10.10 | 1/2 | Novak Djokovic | John Isner | 7-61, 6-2 | | match details | Beijing | Hard |
| 08.10.10 | 1/4 | John Isner | Nikolay Davydenko | 7-62, 6-4 | | match details | ||
| 06.10.10 | 2nd round | John Isner | Philipp Kohlschreiber | 7-63, 3-6, 6-3 | | match details | ||
| 04.10.10 | 1st round | John Isner | Tsung-Hua Yang | 7-65, 6-3 | | match details | ||
| 05.09.10 | 3rd round | Mikhail Youzhny | John Isner | 6-4, 6-77, 7-65, 6-4 | | match details | New York | Hard |
| 03.09.10 | 2nd round | John Isner | Marco Chiudinelli | 6-3, 3-6, 7-67, 6-4 | | match details | ||
| 01.09.10 | 1st round | John Isner | Frederico Gil | 6-4, 6-3, 6-4 | | match details | ||
| 18.08.10 | 2nd round | David Nalbandian | John Isner | 4-5, John Isner - retired | | match details | Cincinnati | Hard |
| 17.08.10 | 1st round | John Isner | Lukasz Kubot | 6-2, 6-3 | | match details | ||
| 05.08.10 | 3rd round | Xavier Malisse | John Isner | 6-4, 3-6, 7-65 | | match details | Washington | Hard |
| 03.08.10 | 2nd round | John Isner | Thiemo de Bakker | 7-66, 7-68 | | match details | ||
| 25.07.10 | fin | Mardy Fish | John Isner | 4-6, 6-4, 7-64 | | match details | Atlanta | Hard |
| 24.07.10 | 1/2 | John Isner | Kevin Anderson | 6-3, 6-77, 6-3 | | match details | ||
| 23.07.10 | 1/4 | John Isner | Michael Russell | 6-1, 6-2 | | match details | ||
| 21.07.10 | 2nd round | John Isner | Gilles Muller | 4-6, 7-66, 7-67 | | match details | ||
| 28.03.10 | 3rd round | Juan Carlos Ferrero | John Isner | 6-2, 3-6, 6-3 | | match details | Miami | Hard |
| 26.03.10 | 2nd round | John Isner | Michael Russell | 7-65, 2-6, 7-65 | | match details | ||
| 17.03.10 | 4th round | Rafael Nadal | John Isner | 7-5, 3-6, 6-3 | | match details | Indian Wells | Hard |
| 16.03.10 | 3rd round | John Isner | Sam Querrey | 7-63, 6-4 | | match details | ||
| 13.03.10 | 2nd round | John Isner | Kevin Anderson | 6-3, 7-5 | | match details | ||
| 24.01.10 | 4th round | Andy Murray | John Isner | 7-64, 6-3, 6-2 | | match details | Melbourne | Hard |
| 22.01.10 | 3rd round | John Isner | Gael Monfils | 6-1, 4-6, 7-64, 7-65 | | match details | ||
| 20.01.10 | 2nd round | John Isner | Louk Sorensen | 6-3, 7-64, 7-5 | | match details | ||
| 19.01.10 | 1st round | John Isner | Andreas Seppi | 6-3, 6-3, 3-6, 5-7, 6-4 | | match details | ||
| 16.01.10 | fin | John Isner | Arnaud Clement | 6-3, 5-7, 7-62 | | match details | Auckland | Hard |
| 14.01.10 | 1/2 | John Isner | Albert Montanes | 6-2, 7-65 | | match details | ||
| 13.01.10 | 2nd round | John Isner | Juan Monaco | 5-7, 6-4, 6-3 | | match details | ||
| 13.01.10 | 1/4 | John Isner | Tommy Robredo | 7-65, 3-6, 6-4 | | match details | ||
| 12.01.10 | 1st round | John Isner | Guillermo Garcia-Lopez | 4-6, 7-63, 6-2 | | match details | ||
| 13.10.09 | 1st round | Lleyton Hewitt | John Isner | 6-2, 6-4 | | match details | Shanghai | Hard |
| 05.10.09 | 1st round | Stan Wawrinka | John Isner | 6-4, 6-4 | | match details |  Tokyo | Hard |
| 07.09.09 | 4th round | Fernando Verdasco | John Isner | 4-6, 6-4, 6-4, 6-4 | | match details | New York | Hard |
| 05.09.09 | 3rd round | John Isner | Andy Roddick | 7-63, 6-3, 3-6, 5-7, 7-65 | | match details | ||
| 03.09.09 | 2nd round | John Isner | Marsel Ilhan | 6-3, 6-4, 7-61 | | match details | ||
| 31.08.09 | 1st round | John Isner | Victor Hanescu | 6-1, 7-614, 7-65 | | match details | ||
| 19.08.09 | 2nd round | Jeremy Chardy | John Isner | 6-71, 6-3, 4-1, John Isner - retired | | match details | Cincinnati | Hard |
| 18.08.09 | 1st round | John Isner | Tommy Haas | 7-65, 5-7, 7-63 | | match details | ||
| 12.08.09 | 2nd round | Mikhail Youzhny | John Isner | 6-78, 6-1, 6-3 | | match details | Montreal | Hard |
| 11.08.09 | 1st round | John Isner | Jesse Levine | 6-3, 6-4 | | match details | ||
| 08.08.09 | 1/2 | Andy Roddick | John Isner | 6-73, 6-2, 7-5 | | match details | Washington | Hard |
| 07.08.09 | 1/4 | John Isner | Tomas Berdych | 6-3, 6-710, 6-2 | | match details | ||
| 06.08.09 | 3rd round | John Isner | Sebastien de Chaunac | 6-2, 6-4 | | match details | ||
| 05.08.09 | 2nd round | John Isner | Jo-Wilfried Tsonga | 4-6, 7-62, 7-64 | | match details | ||
| 03.08.09 | 1st round | John Isner | Andrey Golubev | 7-68, 6-3 | | match details | ||
| 31.07.09 | 1/4 | Carsten Ball | John Isner | 6-4, 6-4 | | match details | Los Angeles | Hard |
| 29.07.09 | 2nd round | John Isner | Marcos Baghdatis | 6-3, 7-611 | | match details | ||
| 28.07.09 | 1st round | John Isner | Benjamin Becker | 7-68, 7-63 | | match details | ||
| 25.07.09 | 1/2 | Robby Ginepri | John Isner | 6-4, 6-3 | | match details | Indianapolis | Hard |
| 24.07.09 | 1/4 | John Isner | Wayne Odesnik | 7-5, 6-72, 7-5 | | match details | ||
| 23.07.09 | 2nd round | John Isner | Denis Istomin | 6-4, 6-4 | | match details | ||
| 20.07.09 | 1st round | John Isner | Josselin Ouanna | 6-1, 7-66 | | match details | ||
| 01.07.09 | 1st round | Ryler Deheart | John Isner | 6-4, 7-64 | | match details | Winnetka Challenger | Hard |
| 25.04.09 | fin | John Isner | Donald Young | 7-5, 6-4 | | match details | Talahassee Challenger | Hard |
| 24.04.09 | 1/2 | John Isner | Danai Udomchoke | 1-6, 6-4, 6-2 | | match details | ||
| 23.04.09 | 1/4 | John Isner | Prakash Amritraj | 6-75, 6-3, 6-4 | | match details | ||
| 22.04.09 | 2nd round | John Isner | Bjorn Rehnquist | 6-1, 7-64 | | match details | ||
| 22.04.09 | 1st round | John Isner | Scoville Jenkins | 6-4, 6-1 | | match details | ||
| 28.03.09 | 2nd round | David Ferrer | John Isner | 6-3, 3-6, 6-2 | | match details | Miami | Hard |
| 26.03.09 | 1st round | John Isner | Sergiy Stakhovsky | 6-4, 6-4 | | match details | ||
| 24.03.09 | qual. | John Isner | Bjorn Phau | 2-6, 7-5, 6-3 | | match details | ||
| 23.03.09 | q 1 | John Isner | Olivier Rochus | 6-4, 7-5 | | match details | ||
| 18.03.09 | 4th round | Juan Martin Del Potro | John Isner | 7-64, 7-63 | | match details | Indian Wells | Hard |
| 17.03.09 | 3rd round | John Isner | Marat Safin | 6-4, 6-4 | | match details | ||
| 15.03.09 | 2nd round | John Isner | Gael Monfils | 6-75, 6-1, 6-4 | | match details | ||
| 13.03.09 | 1st round | John Isner | Christophe Rochus | 6-1, 6-4 | | match details | ||
| 22.02.09 | q 2 | Frank Dancevic | John Isner | 7-65, 6-2 | | match details | Delray Beach | Hard |
| 21.02.09 | q 1 | John Isner | Rohan Bopanna | 6-2, 6-1 | | match details | ||
| 19.01.09 | 1st round | Dominik Hrbaty | John Isner | 7-64, 2-6, 6-2, 7-5 | | match details | Melbourne | Hard |
| 15.01.09 | 1/4 | Robin Soderling | John Isner | 6-4, 6-4 | | match details | Auckland | Hard |
| 14.01.09 | 2nd round | John Isner | Robby Ginepri | 6-4, 6-71, 7-65 | | match details | ||
| 13.01.09 | 1st round | John Isner | Albert Montanes | 7-64, 7-5 | | match details | ||
| 12.01.09 | qual. | John Isner | Thomaz Bellucci | 6-3, 5-7, 7-63 | | match details | ||
| 11.01.09 | q 2 | John Isner | Ivan Navarro | 6-74, 6-4, 7-5 | | match details | ||
| 10.01.09 | q 1 | John Isner | Michael Lammer | 7-65, 6-75, 6-3 | | match details | ||
| 04.01.09 | q 1 | Andrea Stoppini | John Isner | 7-5, 6-3 | | match details | Brisbane | Hard |
| 16.10.08 | 2nd round | Sam Warburg | John Isner | 7-65, 6-4 | | match details | Calabasas | Hard |
| 14.10.08 | 1st round | John Isner | Colin Ebelthite | 6-4, 6-4 | | match details | ||
| 10.10.08 | 1/4 | Wayne Odesnik | John Isner | 6-74, 6-1, 6-0 | | match details | Sacramento | Hard |
| 08.10.08 | 2nd round | John Isner | Benedikt Dorsch | 7-5, 6-4 | | match details | ||
| 06.10.08 | 1st round | John Isner | Colin Ebelthite | 6-1, 6-4 | | match details | ||
| 28.09.08 | fin | John Isner | Frank Dancevic | 7-62, 4-6, 6-2 | | match details | Lubbock | Hard |
| 27.09.08 | 1/2 | John Isner | Giovanni Lapentti | 7-63, 6-4 | | match details | ||
| 26.09.08 | 1/4 | John Isner | Alex Jr. Bogomolov | 7-63, 4-6, 7-65 | | match details | ||
| 24.09.08 | 2nd round | John Isner | Filip Krajinovic | 6-2, 6-4 | | match details | ||
| 22.09.08 | 1st round | John Isner | Lester Cook | 6-71, 6-4, 7-63 | | match details | ||
| 18.09.08 | 1/4 | Benedikt Dorsch | John Isner | 4-6, 7-66, 6-4 | | match details | Waco | Hard |
| 17.09.08 | 2nd round | John Isner | Alberto Francis | 6-4, 6-2 | | match details | ||
| 16.09.08 | 1st round | John Isner | Gregory Ouellette | 6-4, 6-2 | | match details | ||
| 25.08.08 | 1st round | Andreas Beck | John Isner | 7-65, 6-4, 7-63 | | match details | New York | Hard |
| 19.08.08 | 2nd round | Ivo Karlovic | John Isner | 6-74, 6-3, 6-4 | | match details | New Haven | Hard |
| 18.08.08 | 1st round | John Isner | Igor Kunitsyn | 6-4, 6-4 | | match details | ||
| 15.08.08 | 1/4 | Juan Martin Del Potro | John Isner | 6-4, 6-4 | | match details | Washington | Hard |
| 13.08.08 | 2nd round | John Isner | Donald Young | 6-4, 7-64 | | match details | ||
| 11.08.08 | 1st round | John Isner | Marcel Granollers | 6-3, 6-75, 7-61 | | match details | ||
| 05.08.08 | 1st round | Marat Safin | John Isner | 6-3, 6-4 | | match details | Los Angeles | Hard |
| 30.07.08 | 2nd round | Igor Andreev | John Isner | 3-6, 7-68, 7-5 | | match details | Cincinnati | Hard |
| 29.07.08 | 1st round | John Isner | Andrea Stoppini | 7-62, 6-3 | | match details | ||
| 16.07.08 | 2nd round | Tommy Haas | John Isner | 6-3, 6-4 | | match details | Indianapolis | Hard |
| 15.07.08 | 1st round | John Isner | Robert Kendrick | 7-5, 6-4 | | match details | ||
| 27.03.08 | 1st round | Gael Monfils | John Isner | 6-78, 6-3, 6-3 | | match details | Miami | Hard |
| 16.03.08 | 2nd round | Nikolay Davydenko | John Isner | 6-2, 7-63 | | match details | Indian Wells | Hard |
| 14.03.08 | 1st round | John Isner | Simone Bolelli | 6-3, 6-75, 7-62 | | match details | ||
| 06.03.08 | 2nd round | Kevin Anderson | John Isner | 7-62, 7-5 | | match details | Las Vegas | Hard |
| 04.03.08 | 1st round | John Isner | Alejandro Falla | 4-6, 6-3, 6-4 | | match details | ||
| 15.01.08 | 1st round | Fabrice Santoro | John Isner | 6-2, 6-2, 6-4 | | match details | Melbourne | Hard |
| 07.01.08 | qual. | Ivo Minar | John Isner | 7-5, 7-67 | | match details | Sydney | Hard |
| 06.01.08 | q 1 | John Isner | Arnaud Clement | 6-2, 7-65 | | match details | ||
| 06.01.08 | q 2 | John Isner | Boris Pashanski | 6-3, 7-62 | | match details | ||
| 20.10.07 | 1/2 | Robert Kendrick | John Isner | 4-6, 6-3, 7-63 | | match details | Calabasas | Hard |
| 19.10.07 | 1/4 | John Isner | Bobby Reynolds | 7-62, 7-5 | | match details | ||
| 17.10.07 | 2nd round | John Isner | Luka Gregorc | 7-66, 6-4 | | match details | ||
| 15.10.07 | 1st round | John Isner | Izak van der Merwe | 7-5, 6-4 | | match details | ||
| 27.09.07 | 2nd round | Fritz Wolmarans | John Isner | 7-5, 6-4 | | match details | Tulsa | Hard |
| 26.09.07 | 1st round | John Isner | Nathan Healey | 7-65, 6-4 | | match details | ||
| 01.09.07 | 3rd round | Roger Federer | John Isner | 6-74, 6-2, 6-4, 6-2 | | match details | New York | Hard |
| 29.08.07 | 2nd round | John Isner | Rik de Voest | 6-3, 6-3, 7-64 | | match details | ||
| 27.08.07 | 1st round | John Isner | Jarkko Nieminen | 6-74, 7-64, 7-65, 6-4 | | match details | ||
| 22.08.07 | 2nd round | David Ferrer | John Isner | 6-72, 6-2, 6-2 | | match details | New Haven | Hard |
| 21.08.07 | 1st round | John Isner | Benjamin Becker | 6-3, 6-4 | | match details | ||
| 13.08.07 | 1st round | David Ferrer | John Isner | 7-63, 6-3 | | match details | Cincinnati | Hard |
| 05.08.07 | fin | Andy Roddick | John Isner | 6-4, 7-64 | | match details | Washington | Hard |
| 04.08.07 | 1/2 | John Isner | Gael Monfils | 6-74, 7-61, 7-62 | | match details | ||
| 03.08.07 | 1/4 | John Isner | Tommy Haas | 6-4, 6-76, 7-65 | | match details | ||
| 02.08.07 | 3rd round | John Isner | Wayne Odesnik | 6-74, 7-63, 7-62 | | match details | ||
| 01.08.07 | 2nd round | John Isner | Benjamin Becker | 3-6, 7-5, 7-66 | | match details | ||
| 31.07.07 | 1st round | John Isner | Tim Henman | 4-6, 6-4, 7-64 | | match details | ||
| 29.07.07 | fin | John Isner | Brian Wilson | 6-79, 6-3, 6-4 | | match details | Lexington | Hard |
| 28.07.07 | 1/2 | John Isner | Brendan Evans | 7-61, 7-63 | | match details | ||
| 27.07.07 | 1/4 | John Isner | Bruno Echagaray | 7-69, 4-6, 7-63 | | match details | ||
| 26.07.07 | 2nd round | John Isner | Kamil Capkovic | 6-3, 6-4 | | match details | ||
| 23.07.07 | 1st round | John Isner | Kyu-Tae Im | 6-3, 6-74, 6-3 | | match details | ||
| 16.07.07 | 1st round | Brendan Evans | John Isner | 6-4, 6-72, 7-69 | | match details | Aptos | Hard |
| 25.06.07 | 1/2 | John Isner | Adam Kennedy | 6-2, 6-3 | | match details | USA F14 | Hard |
| 25.06.07 | 1st round | John Isner | Jeremiah Fuller | 6-0, 6-1 | | match details | ||
| 25.06.07 | fin | John Isner | Ivan Miranda | 6-4, 7-611 | | match details | ||
| 25.06.07 | 2nd round | John Isner | Miguel Gallardo-Valles | 6-74, 7-65, 6-4 | | match details | ||
| 25.06.07 | 1/4 | John Isner | Wesley Whitehouse | 7-610, 7-65 | | match details | ||
| 25.07.06 | 1st round | Todd Widom | John Isner | 7-65, 6-3 | | match details | Lexington | Hard |
| 17.07.06 | 1st round | Shao-Xuan Zeng | John Isner | 7-61, 7-65 | | match details | USA F18 | Hard |
| 26.06.06 | 1/2 | John Isner | Fabrice Martin | 6-3, 6-4 | | match details | USA F14 | Hard |
| 26.06.06 | 1st round | John Isner | Henry Adjei-Darko | 6-4, 7-64 | | match details | ||
| 26.06.06 | 2nd round | John Isner | Piero Luisi | 6-2, 3-6, 6-4 | | match details | ||
| 26.06.06 | fin | Bruno Echagaray | John Isner | 7-67, 7-5 | | match details | ||
| 26.06.06 | 1/4 | John Isner | Alex Kuznetsov | 6-2, 6-4 | | match details | ||
| 19.06.06 | 2nd round | Fabrice Martin | John Isner | 7-65, 6-4 | | match details | USA F13 | Hard |
| 19.06.06 | 1st round | John Isner | Harsh Mankad | 6-2, 6-3 | | match details | ||
| 22.09.05 | 2nd round | Ramon Delgado | John Isner | 7-64, 6-4 | | match details | Lubbock | Hard |
| 20.09.05 | 1st round | John Isner | Michael Russell | 6-4, 7-5 | | match details | ||
| 19.09.05 | q 1 | John Isner | Adrian Prpic | 7-62, 7-64 | | match details | ||
| 19.09.05 | q 2 | John Isner | Dimitrio Martinez-Castro | 6-3, 7-65 | | match details | ||
| 19.09.05 | qual. | John Isner | Phillip King | 7-611, 6-4 | | match details | ||
| 25.07.05 | 1st round | Jonathan Chu | John Isner | 6-76, 6-3, 6-3 | | match details | USA F19 | Hard |
| 18.07.05 | 2nd round | John Isner | Mikhail Lew | 7-5, 6-1 | | match details | USA F18 | Hard |
| 18.07.05 | 1/4 | Jeremy Wurtzman | John Isner | 7-64, 7-61 | | match details | ||
| 18.07.05 | 1st round | John Isner | Robert Steckley | 6-1, 7-62 | | match details | ||
| 11.07.05 | q 2 | Lesley Joseph | John Isner | 6-4, 6-4 | | match details | Aptos | Hard |
| 11.07.05 | q 1 | John Isner | Kevin Kaiser | 6-4, 6-3 | | match details | ||
| 26.07.04 | q 1 | Thomas Blake | John Isner | 6-1, 6-4 | | match details | Lexington | Hard |
